September 15, 2011

Clostridium to Defeat Cancer

Management of cancer therapy continues to grow more and give hope that these malignant cells can be defeated. Over the past 30 years, cancer treatment has undergone a revolution that was so extraordinary.

If at first cancer therapy based on surgery, radiation, and chemotherapy side effect bad and uncomfortable, the next treatment will become more specific and less interference on quality of life they are forced to live it.

Conservative therapy is still like that make the atomic bomb devastated the entire body to feel the consequences. Patient radiation and chemotherapy, for example, often experience nausea, hair loss, until charred skin. In contrast, more advanced therapies called monoclonal antibodies only shoot targets cancer cells so that, in addition to more effective, side effects also much reduced.

These days, the mass media in Europe was giving place to the researchers at the University of Nottingham, UK, and University of Maastricht, the Netherlands, because of its findings. They managed to manipulate the genetics of soil bacteria that can fight cancer directly at the source.

Ancient Bacteria

Bacteria found in soil was named Clostridium sporogenes. Clostridium is a genus of gram-positive bacteria. As an ancient group of bacteria that has been present on Earth when oxygen-rich atmosphere yet, clostridium requires anaerobic conditions (without oxygen) to produce endospores. The condition is then used to treat cancer experts.

Experts have long understood. Tissue is generally conditioned aerobic or oxygen-containing, while cancer cells are solid, as in breast cancer, brain, and prostate, there is no oxygen. Thus, Clostridium endospores will breed well in a dense network of cancer.

Thus, the experts put the enzyme into the bacterial gene, activating its function as cancer drugs work so endosporanya achieve the conditions without oxygen. Thus, the drugs kill only cancer cells, while cells in healthy tissue would be safe.

Professor Nigel Minton, who led the study, as quoted by BBC News, stated, "The properties owned by clostridium it is actually a common natural phenomenon, but to be exceptional in the treatment of cancer."

Nell Barrie, a senior staff member at the information agency of Cancer Research UK, echoed Minton. He called this finding as the key to cancer prevention have been sought after experts.

Tests on animals had shown encouraging results. Drugs are injected through the bloodstream is only active in the section containing the enzyme triggers. However, Barrie reminded that cancer remains a difficult health problems resolved because of the character of each different cancer cells.

Unfortunately, from the time found this method until it is actually used to treat cancer patients still need a long time. Trials in cancer patients, for example, will begin in 2013.

In monoclonal antibody experience, from when she was found Cesar Milstein and Georges Kohler in Cambridge, England, in 1975, it took about ten years until this treatment method could eventually be used for therapy among medical patients.

In addition to monoclonal antibodies, there is also an anticancer drug that contains a "small molecule". These molecules after entry into the cells to function to block signals from the cell wall receptor called tyrosine kinase domain. By blocking the command signal to the nucleus of a cell to divide, cancer cells can be turned off. Drugs "small molecule" is in between to cope with lung and pancreatic cancer.

Problems with

So many efforts to tackle cancer research because until now the disease is still a one cause of death in the world. According to the World Health Organization (WHO), there are 7.6 million cancer deaths in 2008 and is expected to increase to 11 million deaths by 2030.

The results of all efforts is the variety of treatment methods-conventional or modern-with all its pros and cons. Modern treatment methods are generally effective, but still very expensive. While the conservatives often cause side effects although the cost is relatively cheaper.

In practice, cancer treatment is often combined, both between treatments and between modern and conservative conservative treatment. That's why cancer therapies should be administered by a team with a variety of subspecialty, such as specialist hematology, oncology, radiology, and anatomic pathology.


Clostridium to Defeat Cancer

Management of cancer therapy continues to grow more and give hope that these malignant cells can be defeated. Over the past 30 years, cancer treatment has undergone a revolution that was so extraordinary.

If at first cancer therapy based on surgery, radiation, and chemotherapy side effect bad and uncomfortable, the next treatment will become more specific and less interference on quality of life they are forced to live it.

Conservative therapy is still like that make the atomic bomb devastated the entire body to feel the consequences. Patient radiation and chemotherapy, for example, often experience nausea, hair loss, until charred skin. In contrast, more advanced therapies called monoclonal antibodies only shoot targets cancer cells so that, in addition to more effective, side effects also much reduced.

These days, the mass media in Europe was giving place to the researchers at the University of Nottingham, UK, and University of Maastricht, the Netherlands, because of its findings. They managed to manipulate the genetics of soil bacteria that can fight cancer directly at the source.

Ancient Bacteria

Bacteria found in soil was named Clostridium sporogenes. Clostridium is a genus of gram-positive bacteria. As an ancient group of bacteria that has been present on Earth when oxygen-rich atmosphere yet, clostridium requires anaerobic conditions (without oxygen) to produce endospores. The condition is then used to treat cancer experts.

Experts have long understood. Tissue is generally conditioned aerobic or oxygen-containing, while cancer cells are solid, as in breast cancer, brain, and prostate, there is no oxygen. Thus, Clostridium endospores will breed well in a dense network of cancer.

Thus, the experts put the enzyme into the bacterial gene, activating its function as cancer drugs work so endosporanya achieve the conditions without oxygen. Thus, the drugs kill only cancer cells, while cells in healthy tissue would be safe.

Professor Nigel Minton, who led the study, as quoted by BBC News, stated, "The properties owned by clostridium it is actually a common natural phenomenon, but to be exceptional in the treatment of cancer."

Nell Barrie, a senior staff member at the information agency of Cancer Research UK, echoed Minton. He called this finding as the key to cancer prevention have been sought after experts.

Tests on animals had shown encouraging results. Drugs are injected through the bloodstream is only active in the section containing the enzyme triggers. However, Barrie reminded that cancer remains a difficult health problems resolved because of the character of each different cancer cells.

Unfortunately, from the time found this method until it is actually used to treat cancer patients still need a long time. Trials in cancer patients, for example, will begin in 2013.

In monoclonal antibody experience, from when she was found Cesar Milstein and Georges Kohler in Cambridge, England, in 1975, it took about ten years until this treatment method could eventually be used for therapy among medical patients.

In addition to monoclonal antibodies, there is also an anticancer drug that contains a "small molecule". These molecules after entry into the cells to function to block signals from the cell wall receptor called tyrosine kinase domain. By blocking the command signal to the nucleus of a cell to divide, cancer cells can be turned off. Drugs "small molecule" is in between to cope with lung and pancreatic cancer.

Problems with

So many efforts to tackle cancer research because until now the disease is still a one cause of death in the world. According to the World Health Organization (WHO), there are 7.6 million cancer deaths in 2008 and is expected to increase to 11 million deaths by 2030.

The results of all efforts is the variety of treatment methods-conventional or modern-with all its pros and cons. Modern treatment methods are generally effective, but still very expensive. While the conservatives often cause side effects although the cost is relatively cheaper.

In practice, cancer treatment is often combined, both between treatments and between modern and conservative conservative treatment. That's why cancer therapies should be administered by a team with a variety of subspecialty, such as specialist hematology, oncology, radiology, and anatomic pathology.