Future Prevention And Treatment For Liver Cancer

Prevention

Around the world, the majority liver cancer associated with chronic hepatitis B virus infection. Now, however, all newborns vaccinated against hepatitis B in China and other Asian countries. Therefore, the frequency of chronic hepatitis B virus in future generations will be reduced.

Surgery

Surgery options are limited to individuals whose tumors less than 5 cm and confined to the liver, with no invasion of blood vessels.

Liver resection

The purpose of  liver resection is a complete lifting of the tumor and surrounding liver tissue without leaving any corresponding tumor behind.

Ablation Techniques

Radiofrequency ablation (RFA) therapy / radio frequency ablation therapy

In the U.S., RFA therapy has become the choice of therapy ablation (destruction or destruction of tissue) between surgeons. Surgeons can perform this procedure laparoscopically (through small holes in the abdomen) or during exploration (exploration) open the abdomen. In some instances, the procedure can be performed without opening the abdomen by just using ultrasound for visual guidance.

Chemoembolization (trans-arterial chemoembolization or TACE)

This technique takes advantage of the fact that liver cancer is a tumor that is very vascular (contains many blood vessels) and gets its blood supply exclusively from the hepatic artery branches. This procedure is similar to intra-arterial infusion chemotherapy.

Chemotherapy Systemic (whole body)

Systemic chemotherapeutic agents most commonly used are doxorubicin (Adriamycin) and 5-fluorouracil (5 FU). These drugs are used together or in combination with new agents that are experimental. These drugs are highly toxic and the results have been disappointing. Some studies suggest some benefit with tamoxifen (Nolvadex) but studies that showed no benefit

Treatment Options for Liver Cancer

Options (options) treatment is dictated by the circumstances of liver cancer and the patient's overall condition. The only cure for liver cancer has been proven is a liver transplant for a small tumor (less than 3 cm) of a separate (remote).

Natural History of Liver Cancer

related (eg cirrhosis) at the time of diagnosis. For example, a patient with a tumor 1 cm with no cirrhosis had an opportunity three-year survival greater than 50%, even without treatment. In contrast, a patient with many tumors involving both lobes (lobe) liver (multicentric tumors) with decompensated cirrhosis (signs of liver failure) is not likely last more than six months to live, even with treatment.

Liver biopsy or suction

In theory, a definitive diagnosis of liver cancer is always based on microscopic confirmation (by histology, the science of body tissue). However, some well-differentiated HCC, which means they are formed from liver cells (hepatocytes), which has been developed with full and ripe. Therefore, these cancers can look very similar to liver tissue is not cancerous under a microscope. Moreover, not all pathologists are trained to recognize subtle differences between the liver cancer that are distinguished by good and normal liver tissue. Also, some pathologists can mistake HCC for adenocarcinoma in the liver. An adenocarcinoma is a distinct type of cancer, and as mentioned previously, it originates from outside the liver. Most importantly, a metastatic adenocarcinoma would be treated differently from a primary liver cancer. Therefore, all of this considered, it is important that a pathologist reviewing the liver tissue slices of liver tumors in questionable situations.

Imaging studies for the diagnosis of liver cancer

Imaging studies (imaging) plays a pivotal role in the diagnosis of liver cancer. A good study can provide information such as tumor size, tumor number, and whether the tumor has involved major blood vessels locally or spread outside the liver. There are several types of studies, each has advantages and disadvantages. In practice, several studies combined often complement each other. On the other hand, an X-ray usually is not very helpful, and therefore, not routinely done in improving the diagnosis of liver cancer. Furthermore, there is no practical role for nuclear medical scans of the liver and spleen in the execution of liver cancer. Scan range is not very sensitive and they do not provide any additional information beyond that provided by the scan-scan (ultrasound, CT, and MRI) others.

Diagnosis of Liver Cancer

Blood Test

Liver cancer is not diagnosed by routine blood test, which is a standard panel of liver tests. Diagnosis of liver cancer depends so much on the vigilance of a doctor that filters with a tumor marker (alpha-fetoprotein) in the blood and imaging studies (imaging) of radiology. Because most patients with liver cancer-related liver disease (cirrhosis), liver blood tests they probably are not normal to begin with. If these blood tests become abnormal or worsen due to liver cancer, it usually marks the extensive involvement of liver cancer. At that time, any medical treatment or surgery may be too late.

Symptoms of Liver Cancer

Early symptoms (clinical presentations) of liver cancer is varied. In countries where liver cancer is very common, cancer is commonly found at a very advanced stage of disease for several reasons. For one thing, the area where there is a high frequency of liver cancer are generally the countries that are developing, where access to health services is limited. For this ainnya, For one thing, screening examinations (screening) for patients at risk of developing liver cancer are not available in these areas. In addition, patients from these regions actually have the disease more aggressive liver cancer. With other words, the tumor usually reaches an advanced state and causes symptoms more rapidly. In contrast, patients in areas of low frequency heart cancer tend to have liver cancer tumors that progress more slowly and, therefore, remain without symptoms longer.

Definition of liver cancer (hepatocellular carcinoma, HCC)

One type of cancer is liver cancer. Liver cancer (hepatocellular carcinoma) is a cancer arising from the heart. It is also known as primary liver cancer or hepatoma. Liver-type is formed from different cell types (eg, bile ducts, blood vessels, and fat storage cells). However, liver cells (hepatocytes) make up 80% of liver tissue. Thus, the majority of primary liver cancers (over 90 to 95%) arises from liver cells and is called hepatocellular cancer (hepatocellular cancer) or carcinoma (carcinoma).

Sorafenib Help Liver Cancer Patients

PATIENTS with advanced liver cancer (hepatocellular carcinoma / HCC) have a greater hope to extend and maintain the quality of life. With a focus on cancer therapy using target drug Sorafenib, HCC patients may increase survival by 47 percent.

"Sorafenib has become a standard system for the treatment of advanced stage liver cancer. It is the only therapy that has demonstrated an increased survival rate for patients with liver cancer in the world and also in Indonesia," said Professor Ali Sulaiman SpDP-KGEH, from the Division Hematology Department of Internal Medicine Faculty of Medicine, University of Indonesia Ciptomangunkusumo Hospital (Faculty of medicine / RSCM) in Jakarta, Thursday (26 / 6).

Some Causes Liver Cancer

To date, no single doctor can be sure what causes a person suffering from cancer. Some experts think could only find or figure out the risk factors that are likely to cause a person suffering from cancer.
Anything that increases the likelihood of someone suffering from cancer is called a risk factor, whereas something that decreases the chances of cancer are called protective factors. Several risk factors for cancer could be avoided, but many others can not be avoided altogether.
One risk factor that can be avoided such as smoking while that can not be avoided such as genetic or hereditary factors. Both these factors are the same as a risk factor for cancer but only the cigarette habit that can be avoided.