The conditions that can cause changes in normal cells into cancer cells is hyperplasia, dysplasia, and neoplasia. Hyperplasia is a condition when normal cells in tissue grown in excessive amounts. Dysplasia is a condition when cells grow abnormally and are generally seen a change in the nucleus. At this stage the nucleus size varies, increased mitotic activity, and no characteristic cytoplasm associated with cell differentiation in the network. Neoplasia is the condition of cells in tissues that had proliferated abnormally and invasive properties. Abnormalities of the cell cycle, such as occurs when:
• G1 phase to the phase displacement S.
• Cell cycles occur without being accompanied by activation of transcription factors. Practitioners of thyroid hormone beta1 (TRbeta1) is a transcription factor activated by the hormones T3 and function as a tumor suppressor gene and THRB disorders are often found in cancer.
• Cell cycle occur with irreversible DNA damage.
• Translocation chromosome positions are often found in white blood cell cancers like leukemia or lymphoma, or loss of DNA in a particular domain on the chromosome. In mielogenus chronic leukemia, 95% of patients experienced translocation chromosome 9 and 22, called the Philadelphia chromosome.
Carcinogenesis in humans is a gradual process as a result of exposure to carcinogens that are often encountered in the environment, throughout life, either through consumption, as well as infection. There are four levels of carcinogenesis:
• initiation of tumor
• tumor promotion
• malignant conversion
• tumor progression
Source: http://id.wikipedia.org/wiki/Kanker
• G1 phase to the phase displacement S.
• Cell cycles occur without being accompanied by activation of transcription factors. Practitioners of thyroid hormone beta1 (TRbeta1) is a transcription factor activated by the hormones T3 and function as a tumor suppressor gene and THRB disorders are often found in cancer.
• Cell cycle occur with irreversible DNA damage.
• Translocation chromosome positions are often found in white blood cell cancers like leukemia or lymphoma, or loss of DNA in a particular domain on the chromosome. In mielogenus chronic leukemia, 95% of patients experienced translocation chromosome 9 and 22, called the Philadelphia chromosome.
Carcinogenesis in humans is a gradual process as a result of exposure to carcinogens that are often encountered in the environment, throughout life, either through consumption, as well as infection. There are four levels of carcinogenesis:
• initiation of tumor
• tumor promotion
• malignant conversion
• tumor progression
Source: http://id.wikipedia.org/wiki/Kanker
