Lung
cancer,
also known as a bronchogenic carcinomas ("carcinoma" is another term
for cancer), broadly classified into two types: small cell lung cancers (SCLC)
and non-small cell lung cancers (NSCLC). This classification is based on
microscopic appearance of cancer cells
themselves. Two types of this cancer grow and spread in different ways, making
a distinction between two types is important.
SCLC comprises
about 20% of lung cancers and is the most aggressive and rapidly growing of all
lung cancers. SCLC is strongly associated with smoking, with only 1% of these
tumors that occur in non-smokers. SCLC quickly spread to many places in the
body and most often discovered after they have spread extensively. Referring to
a specific cell type often seen in SCLC, the cancer is sometimes called oat
cell carcinomas.
NSCLC is the
most common lung cancer, covering
about 80% of all lung cancers. NSCLC has three main types are named based on
the type of cells found in tumors:
• Adenocarcinomas are the most common
type of NSCLC seen in the Americas and covers up to 50% of NSCLC. Where
adenocarcinomas associated with smoking like other lung cancers, this type is
mainly observed also in non-smokers who develop lung cancer. Most
adenocarcinomas arise in areas or around the outside of the lungs.
Bronchioloalveolar carcinoma is a subtype of adenocarcinoma that frequently
develops in various places in the lungs and spreads along the walls of
preexisting alveo.
• Squamous cell carcinomas are more
common than previously adenocarcinomas; now, they cover approximately 30% of
NSCLC. Also known as epidermoid carcinomas, squamous cell cancers occur most
often in the center of the chest in the bronchi.
• Large cell carcinomas, sometimes
referred to as carcinoma-carcinoma that can not be differentiated
(undifferentiated carcinomas), the type of NSCLC is the least common.
• mixtures (mixture) of the types of
different NSCLC also found. Other types of cancer can arise in the lung; types
are much less common than NSCLC and SCLC and together cover only 5% -10% of lung cancer:
• Bronchial
carcinoids include up to 5% of lung cancer. These tumors are generally small
(3-4 cm or less) when diagnosed, and most commonly occurs in people under age
40. Not related to smoking, carcinoid tumors can spread, and a small portion of
these tumors release elements that mimic hormones. Carcinoids usually grows and
spreads more slowly than bronchogenic cancers, and many are detected early
enough to agree on the operation of resection.
• Cancer of the
lung supporting tissues such as smooth muscles, blood vessels, or cells
involved in immune response may rarely occur in the lungs.
As discussed
earlier, a cancer that spreads (metastastatic cancers) from other primary
tumors in the body are often found in the lungs. Tumors from anywhere in the
body may spread to the lungs through one of the bloodstream or lymphatic
system, or directly from the adjacent organs. Tumor that has spread (metastatic
tumors) often many, scattered throughout the lung, and concentrated on areas
around than in the central organs.